Clinical reference support

A–a gradient calculator

Calculate estimated alveolar oxygen and the A–a oxygen gradient from simultaneous arterial values. The result is transparent arithmetic, not a diagnosis or treatment recommendation.

Educational support only. Use a simultaneous arterial sample and document inspired oxygen and local pressure.
Scope and limits
  • Requires PaO₂ and PaCO₂ from the same arterial sample; do not substitute venous values.
  • Uses FiO₂, local barometric pressure, PH₂O 47 mmHg, and respiratory quotient 0.8 as explicit calculation assumptions.
  • Does not apply a normal range, identify a pulmonary condition, direct treatment, or retain results.
Source and formula

The veterinary alveolar gas equation is PAO₂ = FiO₂ × (barometric pressure − PH₂O) − PaCO₂/RQ; A–a gradient is PAO₂ − PaO₂. The Association of Veterinary Anaesthetists proceedings and veterinary research document this form. This implementation fixes PH₂O at 47 mmHg and RQ at 0.8; it does not infer clinical meaning from the result.

Formula audit trail

The formula trail appears after valid values are entered.

Sources: Veterinary alveolar-gas equation references. Reviewed July 2026.